Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220313 | 0.89 | TSHR (0.38) | TSHRALDH1A1THRBHSD17B10TDP1 | |
| SCHEMBL22830358 | 0.89 | TSHR (0.38) | TSHRALDH1A1THRBHSD17B10TDP1 | |
| SCHEMBL587102 | 0.89 | TSHR (0.54) | TSHRALDH1A1THRBHSD17B10TDP1 | |
| SCHEMBL4673731 | 0.89 | TSHR (0.38) | TSHRALDH1A1THRBHSD17B10TDP1 | |
| SCHEMBL9202292 | 0.89 | TSHR (0.38) | TSHRALDH1A1THRBHSD17B10TDP1 | |
| SCHEMBL17266588 | 0.87 | TSHR (0.37) | TSHRALDH1A1THRBHSD17B10TDP1 | |
| SCHEMBL4894534 | 0.83 | TSHR (0.34) | TSHRALDH1A1THRBGLO1 | |
| SCHEMBL4894530 | 0.83 | TSHR (0.34) | TSHRALDH1A1THRBGLO1 | |
| SCHEMBL16864194 | 0.82 | NPC1 (0.36) | TSHRALDH1A1LMNA | |
| SCHEMBL1034236 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040524-B1 | AIR-CURING POLYMERS AND A PROCESS FOR PREPARING THEM | MONSANTO COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |
| EP-0040524-A2 | Air-curing polymers and a process for preparing them | MONSANTO COMPANY (US) | 1981-11-25 | — | — | EP | disclosed |