SCHEMBL111265

SCHEMBL111265

CCCC=C(C)C(C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.43
GRIK2 Q13002 1/20 0.43
CHRM1 P11229 1/20 0.34
AKR1A1 P14550 1/20 0.34
CHRM3 P20309 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34
DRD3 P35462 1/20 0.34
SLC6A3 Q01959 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
TSHR P16473 1/20 0.33
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22500760 0.88 GRIK1 (0.46) GRIK1TSHREP300ACE2
SCHEMBL22500759 0.88 GRIK1 (0.46) GRIK1TSHREP300ACE2
SCHEMBL6256858 0.82 GRIK1 (0.39) GRIK1GRIK2CHRM1AKR1A1CHRM3
SCHEMBL11807745 0.82 GRIK1 (0.39) GRIK1GRIK2CHRM1AKR1A1CHRM3
SCHEMBL28457264 0.81 CYP1A2 (0.40) ALDH1A1CYP1A2FNTAFNTB
SCHEMBL31607354 0.80 GRIK1 (0.44) GRIK1GRIK2CHRM1AKR1A1CHRM3
SCHEMBL16893288 0.78 GRIK1 (0.43) GRIK1GRIK2CHRM1AKR1A1CHRM3
SCHEMBL27530274 0.78 GRIK1 (0.43) GRIK1GRIK2CHRM1AKR1A1CHRM3
SCHEMBL1120288 0.77 TP53 (0.33) GRIK1GRIK2ALDH1A1CYP1A2FNTA
SCHEMBL19398819 0.77 GRIK1 (0.46) GRIK1GRIK2CHRM1AKR1A1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022224232-A2 DENTAL ALIGNERS XIA DANQING (US) 2022-10-27 WO claimed
EP-3648720-B1 ABSORBENT DISPOSABLE ARTICLE COMPRISING A POROUS POLYMER-BASED STRUCTURE ESSITY HYGIENE & HEALTH AB (SE) 2021-03-24 EP claimed
EP-2445623-A1 BRANCHED POLYMER DISPERSANTS Unilever PLC (GB) 2012-05-02 EP claimed
EP-2445626-A1 BRANCHED POLYMER DISPERSANTS Unilever PLC (GB) 2012-05-02 EP claimed
EP-2445625-A1 BRANCHED POLYMER DISPERSANTS Unilever PLC (GB) 2012-05-02 EP claimed
WO-2010149957-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2010-12-29 WO claimed
WO-2010149955-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2010-12-29 WO claimed
WO-2010149962-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2010-12-29 WO claimed
WO-2010089575-A1 BRANCHED COPOLYMERS, COMPOSITION AND USES UNILEVER PLC (GB) 2010-08-12 WO claimed
EP-0642535-B1 PROCESS FOR PREPARING LOW DENSITY POROUS CROSS-LINKED POLYMERIC MATERIALS SHELL OIL CO (US) 1996-10-09 EP claimed
EP-0637320-A1 PROCESS FOR PREPARING LOW DENSITY POROUS CROSSLINKED POLYMERIC MATERIALS. SHELL OIL CO (US) 1995-02-08 EP claimed
US-5362613-A Silver halide photographic material having layers including light-sensitive silver halide emulsion layer on support and layer containing cationic high molecular weight compound with quaternized acrylic ester or amide units FUJI PHOTO FILM CO., LTD. (JP) 1994-11-08 US claimed
WO-1994009061-A1 PROCESS FOR PREPARING LOW DENSITY POROUS CROSSLINKED POLYMERIC MATERIALS SHELL OIL COMPANY (US) 1994-04-28 WO claimed
WO-1993024535-A1 PROCESS FOR PREPARING LOW DENSITY POROUS CROSS-LINKED POLYMERIC MATERIALS SHELL OIL COMPANY (US) 1993-12-09 WO claimed
WO-1993021234-A1 PROCESS FOR PREPARING LOW DENSITY POROUS CROSSLINKED POLYMERIC MATERIALS SHELL OIL COMPANY (US) 1993-10-28 WO claimed
US-5252619-A Polymerizing a water-in-oil high internal phase emulsion, curing time of the monomers in the emulsion can be reduced without adversely affecting polymer properties by curing in stages; absorbent materials SHELL OIL COMPANY (US) 1993-10-12 US claimed
US-5210104-A adding an initiator subsequent to formation of a water-in-oil high internal phase emulsion; form absorbent polymeric foams SHELL OIL COMPANY (US) 1993-05-11 US claimed
US-5200433-A Stabilization of a water-in-oil emulsion with a mixture of sorbitan esters surfactants; improved absorption foams SHELL OIL COMPANY (US) 1993-04-06 US claimed
US-5189070-A Polymerizing a water-in-oil highinternal phase emulsion; reduced curing time or curing in multiple stages SHELL OIL COMPANY (US) 1993-02-23 US claimed
EP-0115373-B1 POLYACETAL MOULDING COMPOSITIONS WITH HIGH IMPACT RESISTANCE CELANESE CORPORATION (US) 1990-12-05 EP claimed