Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | SGPL1 | O95470 | 7/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 12/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135537 | 0.95 | CYP3A4 (0.55) | CYP3A4CYP2C8S1PR3SGPL1S1PR1 | |
| SCHEMBL11141347 | 0.95 | CYP3A4 (0.55) | CYP3A4CYP2C8S1PR3SGPL1S1PR1 | |
| SCHEMBL11138293 | 0.94 | CYP3A4 (0.47) | CYP3A4CYP2C8S1PR3SGPL1S1PR1 | |
| SCHEMBL11140238 | 0.94 | CYP3A4 (0.49) | CYP3A4CYP2C8S1PR3SGPL1S1PR1 | |
| SCHEMBL11139727 | 0.93 | CYP3A4 (0.60) | CYP3A4CYP2C8S1PR3SGPL1S1PR1 | |
| SCHEMBL11141411 | 0.93 | CYP3A4 (0.60) | CYP3A4CYP2C8S1PR3SGPL1S1PR1 | |
| SCHEMBL11143869 | 0.92 | CYP3A4 (0.62) | CYP3A4CYP2C8S1PR3SGPL1S1PR1 | |
| SCHEMBL11135076 | 0.92 | CYP3A4 (0.62) | CYP3A4CYP2C8S1PR3SGPL1S1PR1 | |
| SCHEMBL11139590 | 0.92 | CYP3A4 (0.62) | CYP3A4CYP2C8S1PR3SGPL1S1PR1 | |
| SCHEMBL11141325 | 0.92 | CYP3A4 (0.62) | CYP3A4CYP2C8S1PR3SGPL1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4386007-A | ELECTROOPTIC DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-05-31 | — | — | US | disclosed |