Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | PARL | Q9H300 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747444 | 0.86 | POLB (0.44) | POLBPSIP1PARLTSHRSMN1; SMN2 | |
| SCHEMBL2103375 | 0.85 | POLB (0.43) | POLBPSIP1PARLTSHRSMN1; SMN2 | |
| SCHEMBL18139552 | 0.83 | POLB (0.42) | POLBPSIP1PARLTSHRSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL18139371 | 0.83 | POLB (0.42) | POLBPSIP1PARLTSHRSMN1; SMN2 | |
| SCHEMBL18139447 | 0.83 | POLB (0.42) | POLBPSIP1PARLTSHRSMN1; SMN2 | |
| SCHEMBL18140667 | 0.83 | POLB (0.42) | POLBPSIP1PARLTSHRSMN1; SMN2 | |
| SCHEMBL18141291 | 0.83 | POLB (0.42) | POLBPSIP1PARLTSHRSMN1; SMN2 | |
| SCHEMBL18140358 | 0.83 | POLB (0.42) | POLBPSIP1PARLTSHRSMN1; SMN2 | |
| SCHEMBL18140699 | 0.83 | POLB (0.42) | POLBPSIP1PARLTSHRSMN1; SMN2 | |
| SCHEMBL10458162 | 0.82 | STAT3 (0.54) | STAT3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033088-B1 | ANTIMYCOTIC AGENTS | BAYER AG (DE) | 1983-05-25 | — | — | EP | claimed |
| EP-0033088-A2 | Antimycotic agents | BAYER AG (DE) | 1981-08-05 | — | — | EP | claimed |
| US-4386088-A | Combating fungi with α-azolyl-keto derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1983-05-31 | — | — | US | disclosed |
| EP-0033088-B1 | ANTIMYCOTIC AGENTS | BAYER AG (DE) | 1983-05-25 | — | — | EP | disclosed |
| US-4316932-A | Combating fungi with α-azolyl-keto derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1982-02-23 | — | — | US | disclosed |
| EP-0007506-B1 | DERIVATIVES OF ALPHA-AZOLYL KETONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1981-11-18 | — | — | EP | disclosed |
| EP-0007505-B1 | ALPHA-AZOLYL-BETA-HYDROXY-KETONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1981-09-30 | — | — | EP | disclosed |
| US-4291047-A | Combating fungi with α-azolyl-β-hydroxy-ketones | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-22 | — | — | US | disclosed |
| EP-0033087-A2 | Triazolyl-alkandiole derivatives, process for their preparation and their use as fungicides | BAYER AG (DE) | 1981-08-05 | — | — | EP | disclosed |
| EP-0033088-A2 | Antimycotic agents | BAYER AG (DE) | 1981-08-05 | — | — | EP | disclosed |
| EP-0007505-A2 | Alpha-azolyl-beta-hydroxy-ketones, process for their preparation and their use as fungicides | BAYER AG (DE) | 1980-02-06 | — | — | EP | disclosed |
| EP-0007506-A1 | Derivatives of alpha-azolyl ketones, processes for their preparation and their use as fungicides | BAYER AG (DE) | 1980-02-06 | — | — | EP | disclosed |