Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137152 | 1.00 | MEN1 (0.54) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL11138040 | 0.88 | MEN1 (0.66) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL11138038 | 0.88 | MEN1 (0.66) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL11134913 | 0.85 | MEN1 (0.60) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL11134909 | 0.85 | MEN1 (0.60) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL3681189 | 0.85 | MEN1 (0.68) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL3681187 | 0.85 | MEN1 (0.68) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL11040616 | 0.84 | MEN1 (0.62) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL11132575 | 0.84 | MEN1 (0.62) | MEN1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL11132574 | 0.84 | MEN1 (0.62) | MEN1KMT2ALMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1983000334-A1 | PHENYLALKYLOXIRANE CARBOXYLIC ACIDS, PREPARATION AND THERAPEUTICAL USE | KOHL, BERNHARD | 1983-02-03 | — | — | WO | disclosed |