SCHEMBL1114012

SCHEMBL1114012

C=CC=CC=CCC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18658266 1.00
SCHEMBL8389991 0.90
SCHEMBL8389990 0.90
SCHEMBL1001755 0.87
SCHEMBL1001754 0.87
SCHEMBL19736143 0.87 TSHR (0.31)
SCHEMBL28188329 0.87 TSHR (0.31)
SCHEMBL27651160 0.81
SCHEMBL10883381 0.81
SCHEMBL21294345 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111448226-A Polymerization process 埃克森美孚化学专利公司 2020-07-24 CN disclosed
EP-2279174-A2 ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE Genentech, Inc. (US) 2011-02-02 EP disclosed
WO-2009143246-A2 ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE GENENTECH, INC. (US) 2009-11-26 WO disclosed
EP-2061560-A2 BCL INHIBITORS FOR TREATING PLATELET EXCESS Abbott Laboratories (US) 2009-05-27 EP disclosed
WO-2008030836-A2 BCL INHIBITORS TREATING PLATELET EXCESS ABBOTT LABORATORIES (US) 2008-03-13 WO disclosed
EP-0570594-B1 HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE SHIONOGI & CO (JP) 1997-07-30 EP disclosed
US-5534654-A ANTITUMOR, ANTIINFLAMMATORY, INHIBITOR OF LYMPHOCYTE ADHESIVE FACTORS SHIONOGI & CO., LTD. (JP) 1996-07-09 US disclosed
EP-0570594-A1 HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE SHIONOGI & CO., LTD. (JP) 1993-11-24 EP disclosed