Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2966296 | 0.87 | MEN1 (0.48) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11541470 | 0.85 | MEN1 (0.45) | MEN1KMT2AALDH1A1TSHRADORA3 | |
| SCHEMBL11138560 | 0.84 | MEN1 (0.46) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11138355 | 0.84 | MEN1 (0.33) | MEN1KMT2AZDHHC7ALDH1A1 | |
| SCHEMBL7622057 | 0.83 | MEN1 (0.46) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28454991 | 0.82 | MEN1 (0.44) | MEN1KMT2AALDH1A1TSHRADORA3 | |
| SCHEMBL22070605 | 0.80 | MEN1 (0.49) | MEN1KMT2AALDH1A1TSHRADORA3 | |
| SCHEMBL1263510 | 0.79 | MEN1 (0.50) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL11537124 | 0.79 | MEN1 (0.50) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL28753410 | 0.79 | MEN1 (0.43) | MEN1KMT2AKDM4CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4413002-A | Bronchodilating hydantoin derivatives | BEECHAM GROUP LIMITED (GB) | 1983-11-01 | — | — | US | disclosed |
| EP-0014076-B1 | HYDANTOIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1983-02-09 | — | — | EP | disclosed |
| EP-0014076-A2 | Hydantoin derivatives, their preparation and pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1980-08-06 | — | — | EP | disclosed |