Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31179993 | 0.88 | CA12 (0.49) | POLBALDH1A1MAPTCA12CA1 | |
| SCHEMBL11144238 | 0.88 | CA12 (0.49) | POLBALDH1A1MAPTCA12CA1 | |
| SCHEMBL11138571 | 0.87 | HPGD (0.60) | POLBALDH1A1MAPTCA12CA1 | |
| SCHEMBL11754989 | 0.87 | POLB (0.53) | POLBALDH1A1MAPTGAAHDAC1 | |
| SCHEMBL11138092 | 0.83 | HDAC6 (0.51) | POLBCA12CA1CA2CA9 | |
| SCHEMBL20865556 | 0.82 | CA12 (0.44) | POLBALDH1A1MAPTCA12CA1 | |
| SCHEMBL11138778 | 0.81 | APEX1 (0.60) | POLBALDH1A1CA12CA1CA2 | |
| SCHEMBL11135753 | 0.81 | CA12 (0.60) | POLBCA12CA1CA2CA9 | |
| SCHEMBL22203912 | 0.81 | CA12 (0.43) | POLBALDH1A1MAPTCA12CA1 | |
| SCHEMBL11140844 | 0.80 | CA12 (0.48) | CA12CA1CA2CA9HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387105-A | ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY | 1983-06-07 | — | — | US | claimed |
| US-4387105-A | ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY | 1983-06-07 | — | — | US | disclosed |