SCHEMBL1114235

SCHEMBL1114235

CCC(F)C#CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13719164 0.73
SCHEMBL7754043 0.73
SCHEMBL1031752 0.65
SCHEMBL834057 0.65
SCHEMBL1033255 0.65
SCHEMBL964871 0.65
SCHEMBL14890387 0.65
SCHEMBL894787 0.62
SCHEMBL150399 0.60
SCHEMBL27401 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10821196-B2 Substrate based PET imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2020-11-03 US disclosed
US-10799522-B2 Compositions and methods relating to galectin detection WAYNE STATE UNIVERSITY (US) 2020-10-13 US disclosed
US-10639608-B2 System, device and method for preparing tracers and transferring materials during radiosynthesis SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2020-05-05 US disclosed
US-20180221400-A1 COMPOSITIONS AND METHODS RELATING TO GALECTIN DETECTION WAYNE STATE UNIVERSITY 2018-08-09 US disclosed
EP-2279011-B1 SUBSTRATE BASED PET IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA INC (US) 2017-10-25 EP disclosed
EP-2288388-B1 ACHIEVEMENT OF HIGH THERAPEUTIC INDEX THROUGH MOLECULAR IMAGING GUIDED TARGETED DRUG TREATMENT SIEMENS MEDICAL SOLUTIONS (US) 2016-08-31 EP disclosed
EP-2799091-B1 System, device and method for preparing tracers and transferring materials during radiosynthesis LILLY CO ELI (US) 2016-07-13 EP disclosed
US-20150182643-A1 Novel Substrate Based PET Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2015-07-02 US disclosed
US-9005577-B2 Substrate based PET imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2015-04-14 US disclosed
EP-2799091-A2 System, device and method for preparing tracers and transferring materials during radiosynthesis Siemens Medical Solutions USA, Inc. (US) 2014-11-05 EP disclosed
US-20120283490-A1 System, Device and Method for Preparing Tracers and Transferring Materials During Radiosynthesis SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2012-11-08 US disclosed
US-8293206-B2 Achievement of a high therapeutic index through molecular imaging guided targeted drug treatment SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2012-10-23 US disclosed
EP-2511006-A2 System, device and method for preparing tracers and transferring materials during radiosynthesis Siemens Medical Solutions USA, Inc. (US) 2012-10-17 EP disclosed
EP-2288388-A1 ACHIEVEMENT OF HIGH THERAPEUTIC INDEX THROUGH MOLECULAR IMAGING GUIDED TARGETED DRUG TREATMENT Siemens Medical Solutions USA, Inc. (US) 2011-03-02 EP disclosed
EP-2279011-A2 SUBSTRATE BASED PET IMAGING AGENTS Siemens Medical Solutions USA, Inc. (US) 2011-02-02 EP disclosed
US-20100074910-A1 Achievement of a high therapeutic index through molecular imaging guided targeted drug treatment SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2010-03-25 US disclosed
US-20100074843-A1 Novel Substrate Based PET Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2010-03-25 US disclosed
WO-2009148554-A1 ACHIEVEMENT OF HIGH THERAPEUTIC INDEX THROUGH MOLECULAR IMAGING GUIDED TARGETED DRUG TREATMENT SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2009-12-10 WO disclosed
WO-2009134405-A2 NOVEL SUBSTRATE BASED PET IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2009-11-05 WO disclosed