Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 10/20 | 0.61 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11142890 | 1.00 | NOTUM (0.61) | NOTUMHSD17B3HTTTRIM24AVPR1A | |
| SCHEMBL11064543 | 0.85 | NOTUM (0.44) | NOTUMHSD17B3HTTTRIM24HDAC2 | |
| SCHEMBL11136783 | 0.85 | NOTUM (0.44) | NOTUMHSD17B3HTTTRIM24AVPR1A | |
| SCHEMBL9803712 | 0.85 | NOTUM (0.44) | NOTUMHTTHDAC2POLBMAPT | |
| SCHEMBL9803972 | 0.85 | NOTUM (0.44) | NOTUMHTTHDAC2POLBMAPT | |
| SCHEMBL11148186 | 0.85 | NOTUM (0.44) | NOTUMHTTHDAC2POLBMAPT | |
| SCHEMBL11136781 | 0.85 | NOTUM (0.44) | NOTUMHSD17B3HTTTRIM24AVPR1A | |
| SCHEMBL11145384 | 0.85 | NOTUM (0.44) | NOTUMHSD17B3HTTAVPR1AHDAC2 | |
| SCHEMBL11145387 | 0.85 | NOTUM (0.44) | NOTUMHSD17B3HTTAVPR1AHDAC2 | |
| SCHEMBL11137786 | 0.85 | NOTUM (0.44) | NOTUMHSD17B3HTTTRIM24HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421919-A | ANTIEDEMIC, DIURETIC, HYPOTENSIVE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1983-12-20 | — | — | US | disclosed |