Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201884 | 0.80 | KDM4E (0.39) | MEN1KMT2ATHRBCYP3A4HPGD | |
| SCHEMBL28514025 | 0.77 | KDM4E (0.37) | MEN1KMT2ATHRBCYP3A4HPGD | |
| SCHEMBL6968501 | 0.68 | TP53 (0.32) | KDM4EPOLB | |
| SCHEMBL5153861 | 0.67 | CA12 (0.39) | CYP3A4LMNA | |
| SCHEMBL9959156 | 0.67 | TP53 (0.40) | CYP3A4KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28280222 | 0.65 | POLB (0.38) | HPGDKDM4EALDH1A1LMNANPC1 | |
| SCHEMBL7928003 | 0.65 | NOTUM (0.40) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| Sulfurous Acid SCHEMBL29016172 | 0.65 | KDM4E (0.41) | KDM4E | |
| SCHEMBL15100202 | 0.64 | APP (0.44) | MEN1KMT2ACYP3A4HPGDL3MBTL1 | |
| SCHEMBL21408312 | 0.64 | POLB (0.35) | MEN1KMT2ACYP3A4HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369277-A | Pyrrole-stabilized chlorine-containing thermoplastics | CIBA-GEIGY CORPORATION (US) | 1983-01-18 | — | — | US | disclosed |