Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817916 | 0.85 | HDAC4 (0.47) | MEN1KMT2AHDAC4SMN1; SMN2KCNH2 | |
| SCHEMBL1114616 | 0.81 | HDAC4 (0.51) | MEN1KMT2AHDAC4SMN1; SMN2KCNH2 | |
| SCHEMBL1114379 | 0.81 | HDAC4 (0.55) | MEN1KMT2AHDAC4SMN1; SMN2KCNH2 | |
| SCHEMBL1114456 | 0.81 | HDAC4 (0.46) | MEN1KMT2AHDAC4SMN1; SMN2KCNH2 | |
| SCHEMBL1114469 | 0.77 | HDAC4 (0.46) | MEN1KMT2AHDAC4SMN1; SMN2KCNH2 | |
| SCHEMBL1114458 | 0.76 | HDAC4 (0.46) | MEN1KMT2AHDAC4SMN1; SMN2KCNH2 | |
| SCHEMBL8394294 | 0.76 | HDAC4 (0.44) | MEN1KMT2AHDAC4SMN1; SMN2KCNH2 | |
| SCHEMBL1114524 | 0.74 | HDAC4 (0.55) | MEN1KMT2AHDAC4SMN1; SMN2KCNH2 | |
| SCHEMBL8051932 | 0.68 | KCNH2 (0.55) | MEN1KMT2ASMN1; SMN2KCNH2MCHR1 | |
| SCHEMBL4577022 | 0.67 | KCNH2 (0.64) | MEN1KMT2AAPOBEC3AAPOBEC3GKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278879-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | Institute for OneWorld Health (US) | 2011-02-02 | — | — | EP | claimed |
| WO-2009131957-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | claimed |
| EP-2278879-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | Institute for OneWorld Health (US) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009131957-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | disclosed |