Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13247786 | 0.84 | KMT2A (0.50) | MEN1KMT2AALDH1A1HTTL3MBTL1 | |
| SCHEMBL892526 | 0.80 | KMT2A (0.47) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8435748 | 0.78 | HTR2A (0.46) | MEN1KMT2AALDH1A1HTTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8435744 | 0.75 | HTR2A (0.45) | MEN1KMT2AALDH1A1HTTL3MBTL1 | |
| SCHEMBL3237564 | 0.75 | TAAR1 (0.64) | ALDH1A1TSHRMAPK1HTR2CHTR2B | |
| SCHEMBL4498695 | 0.75 | GRIN1 (0.47) | MEN1KMT2AALDH1A1HTTHTR2C | |
| SCHEMBL26416251 | 0.74 | MAPK1 (0.70) | MEN1KMT2AALDH1A1HTTL3MBTL1 | |
| SCHEMBL893046 | 0.74 | KMT2A (0.56) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9492711 | 0.74 | HTR2C (0.48) | HTR2CHTR2BTAAR1CYP1A2CYP3A4 | |
| SCHEMBL13731334 | 0.73 | HTR2C (0.47) | HTR2CHTR2BTAAR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278879-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | Institute for OneWorld Health (US) | 2011-02-02 | — | — | EP | disclosed |