Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910009 | 0.78 | KDM4E (0.52) | TSHRKDM4E | |
| SCHEMBL4640514 | 0.78 | KDM4E (0.52) | TSHRKDM4E | |
| SCHEMBL910007 | 0.78 | KDM4E (0.52) | TSHRKDM4E | |
| SCHEMBL250269 | 0.74 | TSHR (0.38) | TSHRKDM4EALDH1A1 | |
| SCHEMBL250271 | 0.74 | TSHR (0.38) | TSHRKDM4EALDH1A1 | |
| SCHEMBL462908 | 0.71 | TSHR (0.34) | TSHRKDM4EALDH1A1MAPK1TDP1 | |
| SCHEMBL462909 | 0.71 | TSHR (0.34) | TSHRKDM4EALDH1A1MAPK1TDP1 | |
| SCHEMBL6047069 | 0.71 | KDM4E (0.31) | TSHRKDM4E | |
| SCHEMBL18277278 | 0.70 | — | — | |
| SCHEMBL87512 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4374956-A | METAL ADHESIVES | MONSANTO COMPANY (US) | 1983-02-22 | — | — | US | disclosed |
| US-4350740-A | SUBSTITUTED MALEAMIC ACID MODIFIER; ADHESION TO METALS | MONSANTO COMPANY (US) | 1982-09-21 | — | — | US | disclosed |