Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011861 | 1.00 | KMT2A (0.47) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5379789 | 0.86 | KMT2A (0.53) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5379742 | 0.86 | KMT2A (0.53) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5379214 | 0.86 | KMT2A (0.53) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL295762 | 0.86 | KMT2A (0.53) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5385064 | 0.86 | KMT2A (0.53) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL31655442 | 0.85 | CHRM2 (0.43) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL12151312 | 0.85 | CHRM2 (0.50) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL12087990 | 0.85 | CHRM2 (0.50) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7313734 | 0.81 | KMT2A (0.49) | KMT2ACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410532-A | N-Substituted aziridine-2-carboxylic acid derivatives and their immuno-stimulation compositions and methods | BOEHRINGER MANNHEIM GMBH (DE) | 1983-10-18 | — | — | US | disclosed |
| US-4409236-A | N-Substituted aziridine-2-carboxylic acid derivatives and immuno-stimulation composition and method | BOEHRINGER MANNHEIM GMBH (DE) | 1983-10-11 | — | — | US | disclosed |
| US-4321194-A | N-Substituted aziridine-2-carboxylic acid derivatives for immuno stimulation | BOEHRINGER MANNHEIM GMBH (DE) | 1982-03-23 | — | — | US | disclosed |