Acetone

Acetone

SCHEMBL11147103

CC(C)(C)[O-].CC(C)(C)[O-].CC(C)(C)[O-].CC(C)=O.[Al+3]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
CA1 P00915 2/20 0.43
CA4 P22748 2/20 0.38
TSHR P16473 2/20 0.36
THPO P40225 1/20 0.36
FFAR3 O14843 1/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
ALDH1A1 P00352 2/20 0.35
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
MAPT P10636 1/20 0.30
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL14940699 0.88 FFAR3 (0.54) LMNACA1CA4TSHRTHPO
Acetic Acid SCHEMBL14940696 0.88 CA1 (0.61) LMNACA1CA4TSHRTHPO
Acetic Acid SCHEMBL28160629 0.80 CA1 (0.61) LMNACA1CA4TSHRTHPO
Acetic Acid SCHEMBL28142748 0.77 CA1 (0.64) LMNACA1CA4TSHRTHPO
SCHEMBL11063433 0.77
SCHEMBL187645 0.76 TSHR (0.30) TSHR
Acetic Acid SCHEMBL27857590 0.73 CA1 (0.80) LMNACA1CA4TSHRTHPO
Tert-Butanol SCHEMBL8009262 0.73
Bicarbonate SCHEMBL7227703 0.72 CA4 (0.44) CA1CA4TSHRFFAR3LCK
Acetone SCHEMBL9772143 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0024943-B1 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM TORAY INDUSTRIES, INC. (JP) 1983-08-17 EP disclosed
US-4301164-A FOR USE AS ANTIULCER AGENTS, HYPOTENSIVE AGENTS, ANTITHROMBOSIC AGENTS TORAY INDUSTRIES, INC. (JP) 1981-11-17 US disclosed
EP-0024943-A1 5,6,7-Trinor-4,8-inter-m-phenylene PGI2 derivatives and pharmaceutical compositions containing them TORAY INDUSTRIES, INC. (JP) 1981-03-11 EP disclosed