SCHEMBL1114746

SCHEMBL1114746

O=Cc1cnno1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27531080 0.74
SCHEMBL28185567 0.64
SCHEMBL27346904 0.62
SCHEMBL51391 0.61
SCHEMBL27575760 0.60
SCHEMBL16611747 0.58
SCHEMBL27913947 0.58
SCHEMBL685618 0.57
SCHEMBL7238720 0.56
Hydrochloric Acid SCHEMBL27598618 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108349949-A N- substituted indole derivatives as PGE2 receptor modulators 爱杜西亚药品有限公司 2018-07-31 CN claimed
CN-102741240-A Pyrimidine compounds as delta opioid receptor modulators JANSSEN PHARMACEUTICA NV 2012-10-17 CN claimed
JP-2011526284-A 2011-10-06 JP claimed
EP-2318392-A2 PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS IRM LLC (BM) 2011-05-11 EP claimed
EP-2278879-A2 COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES Institute for OneWorld Health (US) 2011-02-02 EP claimed
EP-2214669-A1 CYTOKINE INHIBITORS Hutchison Medipharma Enterprises Limited (BS) 2010-08-11 EP claimed
WO-2010002655-A2 COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS IRM LLC (BM) 2010-01-07 WO claimed
WO-2009131957-A2 COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES INSTITUTE FOR ONEWORLD HEALTH (US) 2009-10-29 WO claimed
CN-101472914-A C-FMS kinase inhibitors JANSSEN PHARMACEUTICA NV (BE) 2009-07-01 CN claimed
WO-2009059162-A1 CYTOKINE INHIBITORS HUTCHISON MEDIPHARMA ENTERPRISES LIMITED (BS) 2009-05-07 WO claimed
CN-101304982-A Process for the preparation of benzotriazepine derivatives JANSSEN PHARMACEUTICA NV (BE) 2008-11-12 CN claimed
CN-1701069-A 3,4-disubstituted pyrroles and their for use in treating inflammatory diseases JANSSEN PHARMACEUTICA NV (BE) 2005-11-23 CN claimed
CN-1678298-A Use of an alpha2delta ligand such as gabapentin or pregabalin for treating ttention deficit hyperactivity disorder WARNER LAMBERT CO (US) 2005-10-05 CN claimed
CN-1625393-A Alpha 2 delta ligands to treat tinnitus WARNER LAMBERT CO (US) 2005-06-08 CN claimed
CN-1512983-A Compounds and compositions as cathepsins inhibitors AXYSҩ�﹫˾ 2004-07-14 CN claimed
CN-1279673-A ((Cyclo) alkyl substituted-.gamma.-aminobutyric acid derivatives (=GABA analogurs), their preparation and their use in the treatment of neurolog disorders WARNER LAMBERT CO (US) 2001-01-10 CN claimed
US-20230331724-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-10-19 US disclosed
US-11731971-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-08-22 US disclosed
CN-1252691-A Use of sulfonyloxadiazolones as microbicides BAYER AG (DE) 2000-05-10 CN disclosed
CN-1167486-A 2- (pyrazol-3-yl) carbapenem derivatives SMITHKLINE BEECHAM PLC (GB) 1997-12-10 CN disclosed