Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720101 | 0.81 | HSP90AA1 (0.55) | TRPV1CNR2HSP90AA1FAAHMEN1 | |
| SCHEMBL27699570 | 0.81 | HSP90AA1 (0.55) | TRPV1CNR2HSP90AA1FAAHMEN1 | |
| SCHEMBL30513275 | 0.80 | TSHR (0.53) | TRPV1CNR2HSP90AA1FAAHMEN1 | |
| SCHEMBL26660363 | 0.78 | MGAM (0.31) | — | |
| SCHEMBL10951627 | 0.78 | HSP90AA1 (0.55) | TRPV1CNR2HSP90AA1FAAHMEN1 | |
| SCHEMBL10957116 | 0.78 | HSP90AA1 (0.55) | TRPV1CNR2HSP90AA1FAAHMEN1 | |
| SCHEMBL9739970 | 0.78 | HSP90AA1 (0.55) | TRPV1CNR2HSP90AA1FAAHMEN1 | |
| SCHEMBL31261502 | 0.78 | HSP90AA1 (0.55) | TRPV1CNR2HSP90AA1FAAHMEN1 | |
| SCHEMBL31261504 | 0.76 | HSP90AA1 (0.52) | TRPV1CNR2HSP90AA1FAAHMEN1 | |
| SCHEMBL11210580 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035291-B1 | PROCESS FOR CARRYING OUT RADICAL REACTIONS AND SHAPED ARTICLES OF THE REACTION PRODUCT | AKZO N.V. (NL) | 1983-05-11 | — | — | EP | disclosed |
| US-4374938-A | HYDROXIMIC ACID DERIVATIVE AS FREE RADICAL INITIATOR | AKZONA INCORPORATED (US) | 1983-02-22 | — | — | US | disclosed |
| US-4347342-A | Process for initiating radical reactions employing hydroximic acid derivatives | AKZONA INCORPORATED (US) | 1982-08-31 | — | — | US | disclosed |