Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146431 | 0.96 | MAPT (0.70) | MAPTLMNASMN1; SMN2HTTPOLB | |
| SCHEMBL11145573 | 0.95 | MAPT (0.72) | MAPTLMNASMN1; SMN2HTTPOLB | |
| SCHEMBL6944865 | 0.86 | MAPT (0.64) | MAPTLMNASMN1; SMN2HTTHCAR3 | |
| SCHEMBL27346954 | 0.83 | MAPT (0.56) | MAPTLMNASMN1; SMN2HTTPOLB | |
| SCHEMBL8578400 | 0.83 | MAPT (0.73) | MAPTLMNASMN1; SMN2HTTPOLB | |
| SCHEMBL6941586 | 0.82 | MAPT (0.58) | MAPTLMNASMN1; SMN2HTTHCAR3 | |
| SCHEMBL6941409 | 0.82 | MAPT (0.58) | MAPTLMNASMN1; SMN2HTTHCAR3 | |
| SCHEMBL6941411 | 0.82 | MAPT (0.58) | MAPTLMNASMN1; SMN2HTTHCAR3 | |
| SCHEMBL7752904 | 0.81 | AKR1C4 (0.67) | MAPTPOLBHCAR3KMT2ARAB9A | |
| SCHEMBL3021466 | 0.81 | MAPT (0.70) | MAPTLMNASMN1; SMN2POLBHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31237-E | 2-Benzoyl-4-nitroanilides and their use as medicaments | PIERRE FABRE S.A. (FR) | 1983-05-10 | — | — | US | disclosed |
| US-4289770-A | HYPNOTIC AGENTS FOR TREATMENT OF INSOMNIA | PIERRE FABRE S.A. (FR) | 1981-09-15 | — | — | US | disclosed |