SCHEMBL11150031

CC[C@H](C)[C@H](NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O)[C@@H](C)O)C(C)C

nearest known ligand 0.74

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	8/20	0.73

▸	NPY4R	P50391	8/20	0.73

▸	NPY5R	Q15761	8/20	0.73

▸	NPY1R	P25929	6/20	0.73

▸	RAMP3	O60896	4/20	0.67

▸	CALCR	P30988	4/20	0.67

▸	TFPI	P10646	4/20	0.64

▸	GLP1R	P43220	2/20	0.62

▸	EP300	Q09472	1/20	0.61

▸	HIF1A	Q16665	1/20	0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11174666	0.93	NPY2R (0.66)	NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30906377	0.93	NPY2R (0.71)	NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30495647	0.93	NPY2R (0.77)	NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL31146614	0.93	NPY2R (0.73)	NPY2RNPY4RNPY5RNPY1RCALCR
SCHEMBL30906478	0.93	NPY2R (0.67)	NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30906497	0.92	NPY2R (0.69)	NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30906569	0.92	NPY2R (0.69)	NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30906464	0.92	NPY2R (0.70)	NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL31182982	0.91	NPY2R (0.73)	NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30607435	0.91	NPY2R (0.76)	NPY2RNPY4RNPY5RNPY1RRAMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0094233-A1	Immune modulator peptides	SCRIPPS CLINIC AND RESEARCH FOUNDATION (US)	1983-11-16	—	—	EP	disclosed
US-4415493-A	POTENTIATION; STIMULANTS; POLYPEPTIDES; ANTICARCINOGENIC AGENTS	SCRIPPS CLINIC AND RESEARCH FOUNDATION (US)	1983-11-15	—	—	US	disclosed