Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11152806 | 1.00 | CYP19A1 (0.56) | CYP19A1NR3C1CYP17A1 | |
| SCHEMBL11155804 | 0.91 | CYP19A1 (0.55) | CYP19A1NR3C1 | |
| SCHEMBL11155808 | 0.91 | CYP19A1 (0.55) | CYP19A1NR3C1 | |
| SCHEMBL11700932 | 0.82 | CYP19A1 (0.56) | CYP19A1NR3C1CYP17A1 | |
| SCHEMBL11700924 | 0.82 | CYP19A1 (0.56) | CYP19A1NR3C1CYP17A1 | |
| SCHEMBL11231087 | 0.80 | CYP19A1 (0.56) | CYP19A1NR3C1CYP17A1 | |
| SCHEMBL10625487 | 0.77 | CYP19A1 (0.67) | CYP19A1NR3C1CYP17A1 | |
| SCHEMBL9521283 | 0.76 | CYP19A1 (0.69) | CYP19A1NR3C1 | |
| SCHEMBL9521280 | 0.76 | CYP19A1 (0.69) | CYP19A1NR3C1 | |
| SCHEMBL11699542 | 0.76 | CYP19A1 (0.57) | CYP19A1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4412955-A | Preparation of corticoids from 17-keto steroids | THE UPJOHN COMPANY (US) | 1983-11-01 | — | — | US | claimed |