Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.56 |
| ▸ | CNR2 | P34972 | 3/20 | 0.56 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11163162 | 1.00 | CNR1 (0.56) | CNR1CNR2EZH2SRC | |
| SCHEMBL11152517 | 0.91 | CNR1 (0.52) | CNR1CNR2EZH2SRC | |
| SCHEMBL11149319 | 0.89 | CNR1 (0.57) | CNR1CNR2EZH2SRC | |
| SCHEMBL11149414 | 0.89 | CNR1 (0.57) | CNR1CNR2EZH2SRC | |
| SCHEMBL11159540 | 0.88 | CNR2 (0.59) | CNR1CNR2EZH2SRC | |
| SCHEMBL11155342 | 0.87 | CNR2 (0.59) | CNR1CNR2EZH2SRC | |
| SCHEMBL11150828 | 0.87 | CNR2 (0.72) | CNR1CNR2 | |
| SCHEMBL11156815 | 0.87 | CNR2 (0.72) | CNR1CNR2 | |
| SCHEMBL11151445 | 0.87 | CNR2 (0.59) | CNR1CNR2EZH2SRC | |
| SCHEMBL11156511 | 0.87 | CNR2 (0.59) | CNR1CNR2EZH2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022634-B1 | ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM | TEIJIN LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |