Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154234 | 1.00 | TDP1 (0.37) | TDP1ALDH1A1TSHRHSD17B10CHRM2 | |
| SCHEMBL10982684 | 0.80 | — | — | |
| SCHEMBL27316167 | 0.77 | TDP1 (0.33) | TDP1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL21861805 | 0.76 | — | — | |
| SCHEMBL9297548 | 0.76 | — | — | |
| SCHEMBL988589 | 0.76 | — | — | |
| SCHEMBL11860983 | 0.74 | TDP1 (0.33) | TDP1ALDH1A1TSHRHSD17B10CHRM2 | |
| SCHEMBL11574649 | 0.73 | — | — | |
| Carbamic Acid SCHEMBL27400526 | 0.73 | TDP1 (0.30) | TDP1 | |
| Methomyl SCHEMBL27111 | 0.73 | TDP1 (0.43) | TDP1ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405796-A | Processes for making phosphorus derivatives of aminothiomethylcarbamates | THE UPJOHN COMPANY (US) | 1983-09-20 | — | — | US | disclosed |
| US-4354975-A | Processes for making phosphorus derivatives of aminothiomethylcarbamates | THE UPJOHN COMPANY (US) | 1982-10-19 | — | — | US | disclosed |
| US-4336207-A | Phosphorus derivatives of aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4279840-A | Processes for making phosphorus containing aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1981-07-21 | — | — | US | disclosed |
| US-4279839-A | Processes for making phosphorus containing aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1981-07-21 | — | — | US | disclosed |
| US-4234521-A | Phosphorus derivatives of aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1980-11-18 | — | — | US | disclosed |