Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640236 | 0.79 | TACR1 (0.49) | — | |
| SCHEMBL23321180 | 0.69 | POLB (0.41) | POLBOPRM1OPRK1KCNH2LMNA | |
| SCHEMBL14457266 | 0.68 | MCL1 (0.48) | CHRM2CHRM3 | |
| SCHEMBL15678324 | 0.68 | MCL1 (0.48) | CHRM2CHRM3 | |
| SCHEMBL18640256 | 0.67 | TACR1 (0.47) | CARM1PRMT6 | |
| SCHEMBL2629514 | 0.66 | CHRM3 (0.53) | CARM1PRMT6HRH3SLC6A2SLC6A3 | |
| SCHEMBL28878770 | 0.65 | GBA1 (0.41) | — | |
| SCHEMBL4855546 | 0.65 | HRH3 (0.74) | CARM1PRMT6HRH3GAASMN1; SMN2 | |
| SCHEMBL10202949 | 0.64 | CHRM3 (0.57) | CARM1PRMT6HRH3SLC6A2SLC6A3 | |
| SCHEMBL22098606 | 0.64 | CHRM3 (0.55) | CARM1PRMT6SLC6A2SLC6A3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023706-B1 | 4-PHENOXY PIPERIDINES, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-03-02 | — | — | EP | disclosed |