Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PPOX | P50336 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881418 | 0.90 | TDP1 (0.61) | TDP1S1PR4MAPTLMNANPC1 | |
| SCHEMBL10893024 | 0.90 | TDP1 (0.55) | TDP1S1PR4MAPTLMNANPC1 | |
| SCHEMBL11149455 | 0.89 | TDP1 (0.60) | TDP1S1PR4MAPTLMNANPC1 | |
| SCHEMBL11878540 | 0.89 | TDP1 (0.57) | TDP1S1PR4MAPTLMNANPC1 | |
| SCHEMBL10344542 | 0.89 | TDP1 (0.54) | TDP1S1PR4MAPTLMNANPC1 | |
| SCHEMBL11882008 | 0.88 | TDP1 (0.58) | TDP1S1PR4MAPTLMNANPC1 | |
| SCHEMBL11742834 | 0.86 | TDP1 (0.57) | TDP1S1PR4MAPTLMNANPC1 | |
| SCHEMBL10847574 | 0.85 | TDP1 (0.65) | TDP1S1PR4MAPTLMNAHPGD | |
| SCHEMBL11349085 | 0.84 | TDP1 (0.56) | TDP1S1PR4MAPTLMNAHPGD | |
| Chlomethoxyfen SCHEMBL8538106 | 0.84 | TDP1 (0.68) | TDP1S1PR4MAPTLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401461-A | PRE- AND POSTEMERGENCE HERBICIDES; RICE | ROHM AND HAAS COMPANY (US) | 1983-08-30 | — | — | US | disclosed |
| US-4039588-A | ALKOXY, AMINO, HALO-, OR CYANO-SUBSTITUTED | ROHM AND HAAS COMPANY (US) | 1977-08-02 | — | — | US | disclosed |