Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 12/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574429 | 0.82 | AKR1C3 (0.58) | POLBLMNAALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL1624921 | 0.81 | SLC6A4 (0.52) | MEN1KMT2AHTTALDH1A1AKR1C3 | |
| SCHEMBL167990 | 0.79 | AKR1C3 (0.46) | HTTALDH1A1AKR1C3AKR1C2PTGS1 | |
| SCHEMBL29009982 | 0.79 | AKR1C3 (0.49) | POLBALDH1A1AKR1C3AKR1C2PTGS1 | |
| SCHEMBL11166575 | 0.79 | AKR1C3 (0.47) | AKR1C3AKR1C2PTGS1AKR1C1AKR1B10 | |
| SCHEMBL11164807 | 0.79 | AKR1C3 (0.47) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL2019275 | 0.77 | AKR1C3 (0.53) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL19182879 | 0.77 | AKR1C3 (0.53) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL4488102 | 0.77 | AKR1C3 (0.44) | POLBHTTLMNAALDH1A1AKR1C3 | |
| SCHEMBL6031404 | 0.75 | CYP3A4 (0.45) | MEN1POLBMAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405639-A | INSECTICIDES; PESTICIDES; MITICIDES; NEMATOCIDES; PARACITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-09-20 | — | — | US | disclosed |
| US-4348323-A | FLUORINE-CONTAINING BENZODIOXINE INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |
| US-4284643-A | Combating arthropods with novel fluorine-containing phenylacetic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |