SCHEMBL11158355

SCHEMBL11158355

[CH2]CCC=C(OCC)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
NPC1 O15118 2/20 0.39
SMN1; SMN2 Q16637 4/20 0.38
LMNA P02545 2/20 0.36
TBXAS1 P24557 1/20 0.36
GAA P10253 2/20 0.36
RAB9A P51151 2/20 0.36
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
POLB P06746 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30116295 0.83 MAPT (0.43) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL11158196 0.82 AKT1 (0.41) MAPTMEN1KMT2ANPC1SMN1; SMN2
SCHEMBL2090769 0.82 MEN1 (0.43) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL22333681 0.82 MEN1 (0.43) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL9403559 0.80 MAPT (0.41) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL29017560 0.78 MAPT (0.47) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL6669479 0.77 MEN1 (0.46) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL21243272 0.77 MEN1 (0.44) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL1274897 0.73 MEN1 (0.42) MAPTALDH1A1MEN1KMT2ANPC1
SCHEMBL4651907 0.73 MEN1 (0.42) MAPTALDH1A1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4411496-A DAP, LCD Device with a bias voltage SHARP KABUSHIKI KAISHA (JP) 1983-10-25 US disclosed