Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073931 | 0.88 | HTR2A (0.38) | HTR2AHTR2CHTR2BALDH1A1SRD5A1 | |
| SCHEMBL24359221 | 0.83 | TSHR (0.47) | HTR2CHTR2BALDH1A1TSHRPDK1 | |
| SCHEMBL24359113 | 0.83 | TSHR (0.47) | HTR2CHTR2BALDH1A1TSHRPDK1 | |
| SCHEMBL24176565 | 0.78 | ESR1 (0.44) | SRD5A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL24176557 | 0.78 | ESR1 (0.44) | SRD5A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL10061190 | 0.78 | ESR1 (0.44) | SRD5A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL11312784 | 0.75 | XIAP (0.34) | HTR2AHTR2CHTR2BALDH1A1SRD5A1 | |
| SCHEMBL11154744 | 0.74 | CHRM2 (0.41) | HTR2AHTR2CHTR2BALDH1A1SRD5A1 | |
| SCHEMBL11152082 | 0.72 | NOTUM (0.48) | ALDH1A1XIAPBIRC2TSHRPDK1 | |
| SCHEMBL9073932 | 0.71 | CHRM2 (0.39) | HTR2AHTR2CHTR2BALDH1A1SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4400318-A | TEXTILES | EASTMAN KODAK COMPANY (US) | 1983-08-23 | — | — | US | disclosed |