Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6724764 | 1.00 | MEN1 (0.42) | MEN1KMT2ANPC1RAB9AIDO1 | |
| Hydrochloric Acid SCHEMBL11394663 | 0.99 | IDO1 (0.43) | MEN1KMT2ANPC1RAB9AIDO1 | |
| Hydrochloric Acid SCHEMBL11394668 | 0.99 | IDO1 (0.43) | MEN1KMT2ANPC1RAB9AIDO1 | |
| SCHEMBL6718484 | 0.84 | MEN1 (0.43) | MEN1KMT2AIDO1TAAR1MTNR1A | |
| SCHEMBL6716437 | 0.82 | HSD17B10 (0.54) | MEN1KMT2AIDO1TAAR1MTNR1A | |
| Hydrochloric Acid SCHEMBL11160606 | 0.81 | HSD17B10 (0.52) | MEN1KMT2AIDO1TAAR1MTNR1A | |
| Hydrochloric Acid SCHEMBL11160610 | 0.81 | HSD17B10 (0.52) | MEN1KMT2AIDO1TAAR1MTNR1A | |
| Hydrochloric Acid SCHEMBL11276991 | 0.79 | KMT2A (0.39) | MEN1KMT2ATAAR1POLBHPGD | |
| Hydrochloric Acid SCHEMBL11277002 | 0.79 | KMT2A (0.39) | MEN1KMT2ATAAR1POLBHPGD | |
| SCHEMBL1133249 | 0.79 | BLM (0.46) | MEN1KMT2ANPC1RAB9AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008657-B1 | ALPHA-VINYL-ALPHA-AMINOACIDS AND THEIR ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1983-03-30 | — | — | EP | disclosed |