Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836628 | 0.84 | MAOB (0.56) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL11167408 | 0.81 | MAOB (0.47) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL11376090 | 0.79 | MAOB (0.50) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL14992983 | 0.78 | MAOB (0.56) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL8035502 | 0.78 | CYP19A1 (0.41) | MAOBCYP19A1 | |
| SCHEMBL13690008 | 0.77 | MAOB (0.48) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL69392 | 0.72 | MAOB (0.61) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL15147107 | 0.72 | MAOB (0.61) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL9819236 | 0.72 | MAOB (0.61) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL23957137 | 0.72 | MAOB (0.43) | MAOBADORA3ARKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0020018-B1 | CHROMAN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-06-01 | — | — | EP | disclosed |
| US-4377629-A | ELECTROGRAPHY USING A HEAT RESISTANT RESIN CONTAINING ELECTRICALLY CONDUCTIVE MATERIAL | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1983-03-22 | — | — | US | disclosed |
| US-4303656-A | ANOREXIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1981-12-01 | — | — | US | disclosed |
| EP-0020018-A1 | Chroman derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-12-10 | — | — | EP | disclosed |