Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148283 | 0.88 | CYP3A4 (0.49) | MAPK14CYP3A4PI4KBNOD1CXCL8 | |
| SCHEMBL4837158 | 0.88 | MAPK14 (0.51) | MAPK14CYP3A4PI4KBNOD1CXCL8 | |
| SCHEMBL11153060 | 0.84 | MAPK14 (0.49) | MAPK14CYP3A4PI4KBNOD1CXCL8 | |
| SCHEMBL11153061 | 0.84 | MAPK14 (0.49) | MAPK14CYP3A4PI4KBNOD1CXCL8 | |
| SCHEMBL11150871 | 0.83 | PI4KB (0.46) | MAPK14CYP3A4PI4KBNOD1CXCL8 | |
| SCHEMBL11150880 | 0.83 | PI4KB (0.46) | MAPK14CYP3A4PI4KBNOD1CXCL8 | |
| SCHEMBL11156981 | 0.82 | MAPK14 (0.45) | MAPK14CYP3A4PI4KBNOD1CXCL8 | |
| SCHEMBL11156976 | 0.82 | MAPK14 (0.45) | MAPK14CYP3A4PI4KBNOD1CXCL8 | |
| SCHEMBL11073939 | 0.79 | PI4KB (0.72) | MAPK14CYP3A4PI4KB | |
| SCHEMBL11144960 | 0.79 | PI4KB (0.52) | MAPK14CYP3A4PI4KBNOD1CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091794-A1 | Process for preparing 1.6-disubstituted 2-aminobenzimidazoles | ELI LILLY AND COMPANY (US) | 1983-10-19 | — | — | EP | disclosed |