Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11166392 | 1.00 | HTR1B (0.47) | HTR1BKDM4EALDH1A1LMNATDP1 | |
| SCHEMBL11156179 | 0.88 | HTR1B (0.52) | HTR1BKDM4EALDH1A1LMNATDP1 | |
| SCHEMBL11156184 | 0.88 | HTR1B (0.52) | HTR1BKDM4EALDH1A1LMNATDP1 | |
| Hydrochloric Acid SCHEMBL11164826 | 0.87 | HTR1B (0.51) | HTR1BKDM4EALDH1A1LMNATDP1 | |
| Hydrochloric Acid SCHEMBL11164829 | 0.87 | HTR1B (0.51) | HTR1BKDM4EALDH1A1LMNATDP1 | |
| SCHEMBL11158383 | 0.84 | HTR1B (0.49) | HTR1BKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL11158379 | 0.84 | HTR1B (0.49) | HTR1BKDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL11157130 | 0.84 | HTR1B (0.49) | HTR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11157128 | 0.84 | HTR1B (0.49) | HTR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11156099 | 0.81 | KDM4E (0.61) | HTR1BKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024567-B1 | 2-(4-AMINOBUTOXY)STILBENES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | MITSUBISHI KASEI CORPORATION (JP) | 1983-02-16 | — | — | EP | disclosed |
| US-4310534-A | ANTICONVULSANTS AND MUSCLE RELAXANTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-01-12 | — | — | US | disclosed |
| EP-0024567-A1 | 2-(4-Aminobutoxy)stilbenes and pharmaceutical compositions comprising these compounds | MITSUBISHI KASEI CORPORATION (JP) | 1981-03-11 | — | — | EP | disclosed |