Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11179135 | 0.99 | ESR1 (0.38) | ESR1ALOX15NPC1MAPTRAB9A | |
| SCHEMBL11193053 | 0.99 | ESR1 (0.38) | ESR1ALOX15NPC1MAPTRAB9A | |
| SCHEMBL11175887 | 0.99 | ESR1 (0.38) | ESR1ALOX15NPC1MAPTRAB9A | |
| SCHEMBL11189796 | 0.99 | ESR1 (0.38) | ESR1ALOX15NPC1MAPTRAB9A | |
| SCHEMBL11171233 | 0.98 | ESR1 (0.38) | ESR1ALOX15NPC1MAPTRAB9A | |
| SCHEMBL11199302 | 0.95 | ESR1 (0.39) | ESR1ALOX15ALDH1A1LMNAMEN1 | |
| SCHEMBL11196479 | 0.92 | ESR1 (0.38) | ESR1ALOX15NPC1MAPTRAB9A | |
| SCHEMBL11186114 | 0.92 | ESR1 (0.38) | ESR1ALOX15NPC1MAPTRAB9A | |
| SCHEMBL11173103 | 0.92 | ESR1 (0.38) | ESR1ALOX15NPC1MAPTRAB9A | |
| SCHEMBL11269039 | 0.92 | ESR1 (0.38) | ESR1ALOX15NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024282-B1 | BENZOYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |