Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 6/20 | 0.48 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA4 | P22748 | 6/20 | 0.48 |
| ▸ | CA5A | P35218 | 6/20 | 0.48 |
| ▸ | CA7 | P43166 | 6/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13871578 | 0.90 | TSHR (0.55) | TSHRKMT2APOLBMEN1USP2 | |
| SCHEMBL13871572 | 0.90 | PTPN1 (0.58) | TSHRKMT2APOLBMEN1USP2 | |
| SCHEMBL4849836 | 0.90 | PTPN1 (0.58) | TSHRKMT2APOLBMEN1USP2 | |
| SCHEMBL5981979 | 0.90 | PTPN1 (0.61) | TSHRKMT2APOLBMEN1USP2 | |
| SCHEMBL14263475 | 0.90 | PTPN1 (0.58) | TSHRKMT2APOLBMEN1USP2 | |
| SCHEMBL5982658 | 0.90 | PTPN1 (0.61) | TSHRKMT2APOLBMEN1USP2 | |
| SCHEMBL8829597 | 0.90 | PTPN1 (0.58) | TSHRKMT2APOLBMEN1USP2 | |
| SCHEMBL4849838 | 0.90 | PTPN1 (0.58) | TSHRKMT2APOLBMEN1USP2 | |
| SCHEMBL22022507 | 0.90 | PTPN1 (0.58) | TSHRKMT2APOLBMEN1USP2 | |
| SCHEMBL5981982 | 0.90 | PTPN1 (0.61) | TSHRKMT2APOLBMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4378369-A | HYPOGLYCEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1983-03-29 | — | — | US | disclosed |