Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11189092 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11180607 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11184526 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11181422 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11175055 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11192739 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11183785 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11177537 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11181386 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11189442 | 1.00 | MEN1 (0.48) | MEN1ALDH1A1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402849-A | DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-09-06 | — | — | US | disclosed |
| US-4381302-A | (6aα,10aα,11aα)-2-(2-Pyridinyl)-1,3,4,6,6a,7,8,9,10,10a,11,11a-dodecahydro-2H-pyrazino]1,2-b]isoquinoline and derivatives | MERCK & CO., INC. (US) | 1983-04-26 | — | — | US | disclosed |