⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675978 | 0.97 | — | — | |
| SCHEMBL1964077 | 0.67 | — | — | |
| SCHEMBL1962357 | 0.65 | — | — | |
| SCHEMBL3086918 | 0.65 | — | — | |
| SCHEMBL592003 | 0.65 | — | — | |
| SCHEMBL25297601 | 0.62 | — | — | |
| SCHEMBL11324609 | 0.62 | — | — | |
| SCHEMBL487409 | 0.62 | — | — | |
| SCHEMBL14575124 | 0.62 | — | — | |
| SCHEMBL9319044 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153667-B2 | ATPase inhibitors; Substituted fluorene or benzenerings joined to an alkylene through a sulfone or sulfoxide linkage; without excessive toxicity, irritation, allergic response etc.; sleep dioredrs like excessive sleepiness; Parkinson's disease; Alzheimer's disease; ADD; ADHA; depression, fatigue | CEPHALON, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-20080070956-A1 | Tricyclic aromatic and bis-phenyl sulfinyl derivatives | CEPHALON, INC. (US) | 2008-03-20 | — | — | US | disclosed |