Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11176958 | 1.00 | TDP1 (0.65) | TDP1LMNAHSD17B10L3MBTL1CTDSP1 | |
| SCHEMBL11188369 | 0.92 | TDP1 (0.64) | TDP1LMNAHSD17B10L3MBTL1CTDSP1 | |
| SCHEMBL11188372 | 0.92 | TDP1 (0.64) | TDP1LMNAHSD17B10L3MBTL1CTDSP1 | |
| SCHEMBL11194560 | 0.92 | TDP1 (0.66) | TDP1LMNAHSD17B10L3MBTL1CTDSP1 | |
| SCHEMBL11183181 | 0.91 | TDP1 (0.68) | TDP1LMNAHSD17B10L3MBTL1CTDSP1 | |
| SCHEMBL11183173 | 0.91 | TDP1 (0.68) | TDP1LMNAHSD17B10L3MBTL1CTDSP1 | |
| SCHEMBL11374304 | 0.91 | TDP1 (0.62) | TDP1LMNAHSD17B10L3MBTL1CTDSP1 | |
| SCHEMBL11181090 | 0.90 | TDP1 (0.67) | TDP1LMNAHSD17B10L3MBTL1CTDSP1 | |
| SCHEMBL11181096 | 0.90 | TDP1 (0.67) | TDP1LMNAHSD17B10L3MBTL1CTDSP1 | |
| SCHEMBL8867974 | 0.90 | TDP1 (0.68) | TDP1LMNAHSD17B10L3MBTL1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379924-A | Cephalosporin derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-04-12 | — | — | US | claimed |