SCHEMBL11178331

SCHEMBL11178331

CCCCCCCCC(Cc1ccccc1)(C(=O)OC1CC(C)(C)NC(C)(C)C1)C(=O)OC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.49
CETP P11597 3/20 0.38
AMPD3 Q01432 1/20 0.38
SLC2A1 P11166 1/20 0.37
PTPRC P08575 1/20 0.37
PTPN2 P17706 1/20 0.37
PTPN1 P18031 1/20 0.37
PTPRB P23467 1/20 0.37
PTPRG P23470 1/20 0.37
ACP1 P24666 1/20 0.37
MMP1 P03956 1/20 0.35
MMP9 P14780 1/20 0.35
MMP13 P45452 1/20 0.35
EZH2 Q15910 2/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 1/20 0.34
KMT2A Q03164 1/20 0.34
EPHX2 P34913 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11171760 0.97 GAA (0.50) GAACETPAMPD3SLC2A1PTPRC
SCHEMBL11455459 0.95 GAA (0.53) GAAAMPD3SLC2A1PTPRCPTPN2
SCHEMBL11174326 0.88 GAA (0.58) GAASLC2A1PTPN2PTPN1PTPRB
SCHEMBL11392491 0.87 GAA (0.54) GAASLC2A1PTPN2PTPN1PTPRB
SCHEMBL11180223 0.87 AMPD3 (0.39) GAACETPAMPD3PTPRCPTPN2
SCHEMBL11170571 0.82 AMPD3 (0.38) GAAAMPD3PTPRCPTPN2PTPN1
SCHEMBL12897908 0.82 KMT2A (0.35) GAAHTTKDM4EKMT2A
SCHEMBL11465589 0.82 AMPD3 (0.39) GAAAMPD3PTPRCPTPN2PTPN1
SCHEMBL11500771 0.82 GAA (0.41) GAAKMT2A
SCHEMBL11171633 0.81 GAA (0.50) GAASLC2A1PTPN2PTPN1PTPRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4369275-A PHOTOSTABILITY FOR POLYMERS CIBA-GEIGY AG (CH) 1983-01-18 US disclosed
US-4293468-A Malonate derivatives as stabilizers for organic materials CIBA-GEIGY AG (CH) 1981-10-06 US disclosed