SCHEMBL11178909

SCHEMBL11178909

CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)OC)[C@@H](O)C[C@H]1O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGFR P43088 8/20 0.81
TBXA2R P21731 3/20 0.81
PTGER1 P34995 3/20 0.81
PTGER3 P43115 3/20 0.81
ALDH1A1 P00352 3/20 0.73
KDM4E B2RXH2 1/20 0.73
HKDC1 Q2TB90 1/20 0.73
TDP1 Q9NUW8 1/20 0.73
SAE1 Q9UBE0 1/20 0.73
UBA2 Q9UBT2 1/20 0.73
LMNA P02545 3/20 0.57
PTGER4 P35408 1/20 0.57
PTGDR Q13258 1/20 0.57
SLCO2A1 Q92959 1/20 0.57
PDE4D Q08499 4/20 0.54
HPGD P15428 2/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
HIF1A Q16665 1/20 0.54
ABCC4 O15439 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11072257 0.92 PTGFR (0.68) PTGFRTBXA2RPTGER1PTGER3ALDH1A1
SCHEMBL10626361 0.92 PTGFR (0.68) PTGFRTBXA2RPTGER1PTGER3ALDH1A1
SCHEMBL10627456 0.92 PTGFR (0.68) PTGFRTBXA2RPTGER1PTGER3ALDH1A1
SCHEMBL10626364 0.92 PTGFR (0.68) PTGFRTBXA2RPTGER1PTGER3ALDH1A1
SCHEMBL9481879 0.92 PTGFR (0.68) PTGFRTBXA2RPTGER1PTGER3ALDH1A1
SCHEMBL9481875 0.92 PTGFR (0.68) PTGFRTBXA2RPTGER1PTGER3ALDH1A1
SCHEMBL10424949 0.92 PTGFR (0.68) PTGFRTBXA2RPTGER1PTGER3ALDH1A1
SCHEMBL10881927 0.92 PTGFR (0.68) PTGFRTBXA2RPTGER1PTGER3ALDH1A1
SCHEMBL10882314 0.92 PTGFR (0.68) PTGFRTBXA2RPTGER1PTGER3ALDH1A1
SCHEMBL10881923 0.92 PTGFR (0.68) PTGFRTBXA2RPTGER1PTGER3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4399147-A Prostaglandin 12 analogues and their pharmaceutical compositions ONO PHARMACEUTICAL CO. LTD. (JP) 1983-08-16 US disclosed