Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11642542 | 0.90 | MAPT (0.33) | MAPTHPGDCYP3A4TSHRCYP1A2 | |
| SCHEMBL11643063 | 0.90 | MAPT (0.33) | MAPTHPGDCYP3A4TSHRCYP1A2 | |
| SCHEMBL11183105 | 0.90 | MAPT (0.33) | MAPTHPGDCYP3A4TSHRCYP1A2 | |
| SCHEMBL11647876 | 0.87 | MAPT (0.32) | MAPTHPGDCYP3A4TSHRCYP1A2 | |
| SCHEMBL11642939 | 0.82 | CYP1A2 (0.38) | MAPTHPGDPOLBCYP3A4TSHR | |
| SCHEMBL8855614 | 0.82 | MAPT (0.52) | MAPTHPGDKDM4EPOLBCYP3A4 | |
| SCHEMBL11644077 | 0.81 | MAPT (0.51) | MAPTHPGDKDM4EPOLBCYP3A4 | |
| SCHEMBL8855484 | 0.81 | MAPT (0.51) | MAPTHPGDKDM4EPOLBCYP3A4 | |
| SCHEMBL8855571 | 0.81 | HTT (0.47) | MAPTHPGDKDM4EPOLBCYP3A4 | |
| SCHEMBL11186264 | 0.78 | MAPT (0.38) | MAPTHPGDKDM4EPOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122184-A | Benzimidazole insecticides | ELI LILLY AND COMPANY (US) | 1978-10-24 | — | — | US | claimed |
| US-4421759-A | Methods for controlling fire ants | ELI LILLY AND COMPANY (US) | 1983-12-20 | — | — | US | disclosed |
| US-4122184-A | Benzimidazole insecticides | ELI LILLY AND COMPANY (US) | 1978-10-24 | — | — | US | disclosed |
| US-3980784-A | Control of animal parasites with benzimidazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | disclosed |