SCHEMBL11186554

SCHEMBL11186554

CCn1c2cc(Br)ccc2c2ccc(C=O)cc21

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 5/20 0.52
ALDH1A3 P47895 3/20 0.43
ALDH1A1 P00352 4/20 0.41
ALDH3A1 P30838 2/20 0.41
CYP2A6 P11509 3/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
PKM P14618 1/20 0.38
HTT P42858 1/20 0.38
PTGES O14684 1/20 0.37
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
SRC P12931 2/20 0.36
TSPO P30536 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30958190 0.93 PTGER4 (0.63) PTGER4ALDH1A3ALDH1A1KDM4EPOLB
SCHEMBL24811505 0.93 PTGER4 (0.63) PTGER4ALDH1A3ALDH1A1KDM4EPOLB
SCHEMBL18104492 0.90 PTGER4 (0.61) PTGER4ALDH1A3ALDH1A1ALDH3A1CYP2A6
SCHEMBL29556340 0.85 MAPT (0.44) PTGER4ALDH1A1KDM4EHTTPTGES
SCHEMBL19056399 0.85 MAPT (0.44) PTGER4ALDH1A1KDM4EHTTPTGES
SCHEMBL16066019 0.84 PTGER4 (0.68) PTGER4ALDH1A1KDM4EPOLBPKM
SCHEMBL30061939 0.84 PTGER4 (0.68) PTGER4ALDH1A1KDM4EPOLBPKM
SCHEMBL7172636 0.83 PTGER4 (0.61) PTGER4ALDH1A1KDM4EPOLBPKM
SCHEMBL31222144 0.83 PTGER4 (0.61) PTGER4ALDH1A1KDM4EPOLBPKM
SCHEMBL2584799 0.77 MAPT (0.56) PTGER4ALDH1A1KDM4EPOLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US disclosed
US-4340624-A STYRYL-LIKE COMPOUNDS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-07-20 US disclosed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 US disclosed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US disclosed
US-4139274-A Apparatus for changing color MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-02-13 US disclosed
US-4003633-A Color display device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-01-18 US disclosed