Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 2/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11177134 | 0.87 | TSHR (0.41) | PDE1APDE1BPDE1CKDM4EALDH1A1 | |
| SCHEMBL11182845 | 0.86 | PDE5A (0.39) | PDE1APDE1BPDE1CKDM4EALDH1A1 | |
| SCHEMBL11178335 | 0.86 | PDE5A (0.38) | PDE1APDE1BPDE1CKDM4EALDH1A1 | |
| SCHEMBL11181997 | 0.86 | NPC1 (0.41) | PDE1AKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL11179554 | 0.85 | PDE5A (0.36) | PDE1APDE1BPDE1CKDM4EALDH1A1 | |
| SCHEMBL11173677 | 0.84 | PTGDR2 (0.38) | KDM4EALDH1A1LMNACYP3A4NR1I2 | |
| SCHEMBL11181993 | 0.84 | CYP3A4 (0.38) | PDE1AKDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL11178895 | 0.82 | PDE5A (0.41) | PDE1AKDM4EALDH1A1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL11190666 | 0.81 | PDE5A (0.40) | PDE1APDE1BPDE1CKDM4EALDH1A1 | |
| SCHEMBL11177813 | 0.80 | CYP3A4 (0.39) | KDM4EALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4367230-A | ANTIANOXIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1983-01-04 | — | — | US | disclosed |