Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.62 |
| ▸ | PGR | P06401 | 3/20 | 0.62 |
| ▸ | PPARG | P37231 | 3/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.59 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.59 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | APEX1 | P27695 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11184710 | 0.89 | NR1I2 (0.61) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11194342 | 0.89 | NR1I2 (0.62) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10832993 | 0.89 | NR1I2 (0.68) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11146666 | 0.87 | NR1I2 (0.56) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10416383 | 0.87 | NR1I2 (0.56) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11146670 | 0.87 | NR1I2 (0.56) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL8747445 | 0.87 | NR1I2 (0.57) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10833294 | 0.87 | NR1I2 (0.64) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10831937 | 0.87 | NR1I2 (0.64) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10337674 | 0.87 | NR1I2 (0.56) | NR1I2PGRPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379739-A | Electrolytic reduction of cephalosporin p-nitrobenzyl esters | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |
| EP-0038626-A1 | A process for electrolytic reduction of cephalosporin p-nitrobenzyl esters | ELI LILLY AND COMPANY (US) | 1981-10-28 | — | — | EP | disclosed |