Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.41 |
| ▸ | EYA2 | O00167 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372623 | 0.83 | AR (0.47) | ARMRGPRX4SMN1; SMN2ALDH1A1SLC22A12 | |
| SCHEMBL1197429 | 0.83 | CYP1A2 (0.57) | ARMRGPRX4SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11096810 | 0.82 | AR (0.49) | ARSMN1; SMN2ALDH1A1SLC22A12CYP19A1 | |
| SCHEMBL11182601 | 0.82 | AR (0.46) | ARMRGPRX4ALDH1A1SLC22A12TSHR | |
| SCHEMBL7486810 | 0.81 | POLB (0.54) | ARSMN1; SMN2ALDH1A1CYP19A1CYP3A4 | |
| SCHEMBL11176242 | 0.80 | MRGPRX4 (0.47) | ARMRGPRX4SMN1; SMN2ALDH1A1SLC22A12 | |
| SCHEMBL30487032 | 0.80 | CYP19A1 (0.58) | ARSMN1; SMN2ALDH1A1CYP19A1CYP3A4 | |
| SCHEMBL9826918 | 0.80 | MRGPRX4 (0.63) | MRGPRX4TSHRLMNAL3MBTL1STK39 | |
| SCHEMBL17818514 | 0.80 | CYP19A1 (0.58) | ARSMN1; SMN2ALDH1A1CYP19A1CYP3A4 | |
| SCHEMBL11094525 | 0.79 | SCN9A (0.51) | ARL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4394327-A | THIOESTERS | CIBA-GEIGY CORPORATION (US) | 1983-07-19 | — | — | US | disclosed |