Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dulofibrate SCHEMBL2110601 | 0.83 | PPARA (0.68) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| SCHEMBL24445155 | 0.81 | ELANE (0.56) | CYP3A4MEN1MAPTKMT2ACYP2C9 | |
| SCHEMBL25209491 | 0.78 | PPARA (0.43) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| SCHEMBL987605 | 0.78 | HRH3 (0.43) | MEN1MAPTKMT2AL3MBTL1BLM | |
| SCHEMBL1102242 | 0.76 | SMN1; SMN2 (0.45) | PPARACYP3A4TSHRMEN1MAPT | |
| Propionic Acid SCHEMBL27835649 | 0.74 | PPARA (0.59) | PPARACYP1A2CYP3A4TSHRABCB11 | |
| Bicarbonate SCHEMBL6204994 | 0.74 | BCL2L1 (0.56) | KMT2AL3MBTL1SMN1; SMN2TDP1BCL2L1 | |
| SCHEMBL9938123 | 0.74 | BCL2L1 (0.52) | CYP2C19KMT2AL3MBTL1CYP2C9SMN1; SMN2 | |
| Methyl Alcohol SCHEMBL28438875 | 0.73 | SLC18A3 (0.54) | SMN1; SMN2LSSALDH1A1BCL2L1MCL1 | |
| SCHEMBL11598248 | 0.73 | PPARA (0.47) | PPARACYP1A2CYP3A4HTR2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4412998-A | ANTILIPEMIC | MERZ & COMPANY (DE) | 1983-11-01 | — | — | US | disclosed |