Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429429 | 0.89 | CYP1A2 (0.69) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11427771 | 0.86 | MEN1 (0.62) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL6881555 | 0.84 | MEN1 (0.62) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL10893771 | 0.83 | ESRRG (0.57) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL8356134 | 0.83 | KCNK3 (0.63) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11203123 | 0.82 | ESRRG (0.56) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL10384848 | 0.82 | KCNK3 (0.58) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL8710919 | 0.80 | MEN1 (0.80) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11197369 | 0.80 | NPC1 (0.67) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11427459 | 0.80 | KMT2A (0.61) | MEN1KMT2AMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4373102-A | Isoindoline dyes, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1983-02-08 | — | — | US | disclosed |
| US-4240959-A | FOR ACRYLONITRILE POLYMER OR COPOLYMER FIBERS; FASTNESS | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1980-12-23 | — | — | US | disclosed |