Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.62 |
| ▸ | RELA | Q04206 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817443 | 1.00 | RARB (0.64) | RARBMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL11181528 | 0.97 | MAPT (0.64) | RARBMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL9817442 | 0.95 | RARB (0.70) | RARBMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL9817412 | 0.95 | RARB (0.70) | RARBMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL9817695 | 0.95 | RARB (0.70) | RARBMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL9817469 | 0.95 | RARB (0.70) | RARBMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL9817575 | 0.95 | RARB (0.70) | RARBMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL9817440 | 0.95 | RARB (0.70) | RARBMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL9817342 | 0.95 | RARB (0.70) | RARBMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL9817321 | 0.95 | RARB (0.70) | RARBMAPTSMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025119-A1 | Nematic crystalline-liquid 5-alkyl-2-(4-acyloxyphenyl)-pyrimidines for opto-electronic arrangements and process for their preparation | VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) | 1981-03-18 | — | — | EP | claimed |
| EP-0025119-B1 | NEMATIC CRYSTALLINE-LIQUID 5-ALKYL-2-(4-ACYLOXYPHENYL)-PYRIMIDINES FOR OPTO-ELECTRONIC ARRANGEMENTS AND PROCESS FOR THEIR PREPARATION | VEB Werk Für Fernsehelektronik im VEB Kombinat Mikroelektronik (DD) | 1983-05-25 | — | — | EP | disclosed |