Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.59 |
| ▸ | EBP | Q15125 | 4/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10846021 | 0.82 | ACACB (0.42) | MCHR1EBPSIGMAR1ACACBCYP2D6 | |
| SCHEMBL6724461 | 0.80 | MAPT (0.50) | ACACBMAPT | |
| SCHEMBL6324406 | 0.79 | NR5A1 (0.56) | HTTLTA4HMAPTKDM4E | |
| SCHEMBL6320559 | 0.79 | NR5A1 (0.56) | HTTLTA4HMAPTKDM4E | |
| SCHEMBL9706125 | 0.79 | EBP (0.72) | MCHR1EBPSIGMAR1CYP2D6HTT | |
| SCHEMBL11197136 | 0.78 | MCHR1 (0.70) | MCHR1EBPSIGMAR1ACACBCYP2D6 | |
| SCHEMBL10970158 | 0.78 | MCHR1 (0.91) | MCHR1EBPSIGMAR1ACACBCYP2D6 | |
| SCHEMBL10969368 | 0.77 | MCHR1 (0.68) | MCHR1EBPSIGMAR1ACACBCYP2D6 | |
| SCHEMBL2326599 | 0.76 | MCHR1 (0.62) | MCHR1EBPSIGMAR1ACACBCYP2D6 | |
| SCHEMBL6719797 | 0.76 | MAPT (0.47) | ACACBMAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4412856-A | POSTERMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1983-11-01 | — | — | US | disclosed |