Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11186700 | 0.98 | ESR2 (0.49) | ESR2BACE1 | |
| SCHEMBL11199009 | 0.91 | ESR2 (0.58) | ESR2BACE1NPC1CASP3RAB9A | |
| SCHEMBL11193766 | 0.89 | ESR2 (0.56) | ESR2BACE1NPC1CASP3RAB9A | |
| SCHEMBL11189203 | 0.87 | ESR2 (0.47) | ESR2BACE1NPC1CASP3RAB9A | |
| SCHEMBL11191403 | 0.85 | ESR2 (0.46) | ESR2BACE1NPC1CASP3RAB9A | |
| SCHEMBL11197977 | 0.85 | ESR2 (0.44) | ESR2BACE1 | |
| SCHEMBL10928954 | 0.84 | ESR2 (0.51) | ESR2BACE1NPC1CASP3RAB9A | |
| SCHEMBL11199001 | 0.84 | ESR2 (0.45) | ESR2BACE1NPC1CASP3RAB9A | |
| SCHEMBL11199923 | 0.83 | ESR2 (0.43) | ESR2BACE1 | |
| SCHEMBL11190162 | 0.83 | ESR2 (0.44) | ESR2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030277-B1 | PARTIALLY HYDROGENATED OLIGO-1,4-PHENYLENES, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING DEVICE | MERCK PATENT GmbH (DE) | 1983-07-27 | — | — | EP | disclosed |
| US-4331552-A | Liquid crystalline, partially hydrogenated oligo-1,4-phenylenes and dielectrics and electro-optical display elements containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-25 | — | — | US | disclosed |
| EP-0030277-A1 | Partially hydrogenated oligo-1,4-phenylenes, dielectrics containing them and electro-optical indicating device | MERCK PATENT GmbH (DE) | 1981-06-17 | — | — | EP | disclosed |