Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11190514 | 1.00 | ACE (0.55) | ACE | |
| SCHEMBL11192048 | 0.87 | ACE (0.43) | ACE | |
| SCHEMBL11194364 | 0.83 | ACE (0.52) | ACE | |
| SCHEMBL11194371 | 0.81 | GRIN2B (0.37) | ACE | |
| SCHEMBL11382386 | 0.81 | ACE (0.52) | ACE | |
| SCHEMBL11100929 | 0.81 | HSD17B10 (0.52) | ACE | |
| SCHEMBL11197163 | 0.80 | ACE (0.51) | ACE | |
| SCHEMBL11065988 | 0.77 | ACE (0.67) | ACE | |
| SCHEMBL683556 | 0.77 | ACE (0.67) | ACE | |
| SCHEMBL8829150 | 0.76 | HSD17B10 (0.43) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410542-A | HYPOTENSIVE AGENTS, PYRROLINE-1,2-DICARBOXYLIC ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| US-4347371-A | HYPERTENSIVE AGENTS; ANTIDIABETIC AGENTS; VISION DEFECTS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-08-31 | — | — | US | disclosed |